Loss of nucleus accumbens low-frequency fluctuations is a signature of chronic pain
Volume: 117, Issue: 18, Pages: 10015 - 10023
Published: Apr 20, 2020
Abstract
Chronic pain is a highly prevalent disease with poorly understood pathophysiology. In particular, the brain mechanisms mediating the transition from acute to chronic pain remain largely unknown. Here, we identify a subcortical signature of back pain. Specifically, subacute back pain patients who are at risk for developing chronic pain exhibit a smaller nucleus accumbens volume, which persists in the chronic phase, compared to healthy controls....
Paper Details
Title
Loss of nucleus accumbens low-frequency fluctuations is a signature of chronic pain
Published Date
Apr 20, 2020
Volume
117
Issue
18
Pages
10015 - 10023
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