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doi.org/10.1128/mbio.00602-20

Simian Immunodeficiency Virus-Infected Memory CD4 + T Cells Infiltrate to the Site of Infected Macrophages in the Neuroparenchyma of a Chronic Macaque Model of Neurological Complications of AIDS

..., Vanessa M. Hirsch
59
MBio6.40
Volume: 11, Issue: 2
Published: Apr 28, 2020
Abstract
Simian immunodeficiency virus (SIV)-infected nonhuman primates can serve as a relevant model for AIDS neuropathogenesis. Current SIV-induced encephalitis (SIVE)/neurological complications of AIDS (neuroAIDS) models are generally associated with rapid progression to neuroAIDS, which does not reflect the tempo of neuroAIDS progression in humans. Recently, we isolated a neuropathogenic clone, SIVsm804E-CL757 (CL757), obtained from an SIV-infected...
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Paper Details
Title
Simian Immunodeficiency Virus-Infected Memory CD4 + T Cells Infiltrate to the Site of Infected Macrophages in the Neuroparenchyma of a Chronic Macaque Model of Neurological Complications of AIDS
DOI
doi.org/10.1128/mbio.00602-20
Published Date
Apr 28, 2020
Journal
MBio
Volume
11
Issue
2
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