Inhibitory effects of 5-heptadecylresorcinol on the proliferation of human MCF-7 breast cancer cells through modulating PI3K/Akt/mTOR pathway

Volume: 69, Pages: 103946 - 103946
Published: Jun 1, 2020
Abstract
The effect of 5-heptadecylresorcinol (AR-C17) on the proliferation of human MCF-7 breast cancer cells was investigated in the present study. The results showed that AR-C17 treatment significantly suppressed MCF-7 cells proliferation, trigged intracellular ROS generation and decreased SOD2 expression. Furthermore, AR-C17 treatment could lead to MCF-7 cells apoptosis as evidenced by the activation of Bax/Bcl-2 expression ratio, active caspase...
Paper Details
Title
Inhibitory effects of 5-heptadecylresorcinol on the proliferation of human MCF-7 breast cancer cells through modulating PI3K/Akt/mTOR pathway
Published Date
Jun 1, 2020
Volume
69
Pages
103946 - 103946
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