Patterns of chromosome 18 loss of heterozygosity in multifocal ileal neuroendocrine tumors
Abstract
Ileal neuroendocrine tumors (NETs) represent the most common neoplasm of the small intestine. Although up to 50% of patients with ileal NETs are diagnosed with multifocal disease, the mechanisms by which multifocal ileal NETs arise are not yet understood. In this study, we analyzed genome-wide sequencing data to examine patterns of copy number variation in 40 synchronous primary ileal NETs derived from three patients. Chromosome (chr) 18 loss of...
Paper Details
Title
Patterns of chromosome 18 loss of heterozygosity in multifocal ileal neuroendocrine tumors
Published Date
Apr 27, 2020
Volume
59
Issue
9
Pages
535 - 539
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