Enhancement of abiraterone acetate oral bioavailability by supersaturated-silica lipid hybrids

Volume: 582, Pages: 119264 - 119264
Published: May 1, 2020
Abstract
Abiraterone acetate (AbA) has an oral bioavailability of null null An oral pharmacokinetic study was conducted in fasted Sprague-Dawley rats. Suspensions of the formulations were administered via oral gavage at an AbA dose of 25 mg/kg. Plasma samples were collected and analyzed for drug content. null SLH with a saturation level of 90% Seq enhanced the oral bioavailability of unformulated AbA by 31-fold, and super-SLH with saturation levels of...
Paper Details
Title
Enhancement of abiraterone acetate oral bioavailability by supersaturated-silica lipid hybrids
Published Date
May 1, 2020
Volume
582
Pages
119264 - 119264
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