Targeting the PI3K pathway and DNA damage response as a therapeutic strategy in ovarian cancer
Abstract
Ovarian cancer is the most lethal gynecological malignancy worldwide although exponential progress has been made in its treatment over the last decade. New agents and novel combination treatments are on the horizon. Among many new drugs, a series of PI3K/AKT/mTOR pathway (referred to as the PI3K pathway) inhibitors are under development or already in clinical testing. The PI3K pathway is frequently upregulated in ovarian cancer and activated...
Paper Details
Title
Targeting the PI3K pathway and DNA damage response as a therapeutic strategy in ovarian cancer
Published Date
Jun 1, 2020
Journal
Volume
86
Pages
102021 - 102021
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