Longitudinal Assessment of Multiple Sclerosis with the Brain‐Age Paradigm
Abstract
Objective During the natural course of multiple sclerosis (MS), the brain is exposed to aging as well as disease effects. Brain aging can be modeled statistically; the so‐called “brain‐age” paradigm. Here, we evaluated whether brain‐predicted age difference (brain‐PAD) was sensitive to the presence of MS, clinical progression, and future outcomes. Methods In a longitudinal, multicenter sample of 3,565 magnetic resonance imaging (MRI) scans, in...
Paper Details
Title
Longitudinal Assessment of Multiple Sclerosis with the Brain‐Age Paradigm
Published Date
May 6, 2020
Journal
Volume
88
Issue
1
Pages
93 - 105
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