Tunable genetic devices through simultaneous control of transcription and translation
Abstract
Synthetic genetic circuits allow us to modify the behavior of living cells. However, changes in environmental conditions and unforeseen interactions with the host cell can cause deviations from a desired function, resulting in the need for time-consuming reassembly to fix these issues. Here, we use a regulatory motif that controls transcription and translation to create genetic devices whose response functions can be dynamically tuned. This...
Paper Details
Title
Tunable genetic devices through simultaneous control of transcription and translation
Published Date
Apr 29, 2020
Journal
Volume
11
Issue
1
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