Review paper
Replication Stress, DNA Damage, Inflammatory Cytokines and Innate Immune Response
Abstract
Complete and accurate DNA replication is essential to genome stability maintenance during cellular division. However, cells are routinely challenged by endogenous as well as exogenous agents that threaten DNA stability. DNA breaks and the activation of the DNA damage response (DDR) arising from endogenous replication stress have been observed at pre- or early stages of oncogenesis and senescence. Proper detection and signalling of DNA damage are...
Paper Details
Title
Replication Stress, DNA Damage, Inflammatory Cytokines and Innate Immune Response
Published Date
Apr 9, 2020
Journal
Volume
11
Issue
4
Pages
409 - 409
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