Match!

Constitutional symptoms, pathologic PET-CT.

Published on Apr 1, 2020in Cleveland Clinic Journal of Medicine1.855
· DOI :10.3949/CCJM.87A.19053
Julia L. Riera , Jorge L. Musuruana6
Estimated H-index: 6
+ 1 AuthorsJavier A. Cavallasca7
Estimated H-index: 7
Abstract
A 74-year-old woman presented with a 6-month history of malaise, generalized fatigue, significant unintentional weight loss, and night sweats, as well as pain, weakness, and stiffness in the shoulder girdle most severe in the morning. She reported no headache, visual disturbances, or jaw
  • References (6)
  • Citations (0)
📖 Papers frequently viewed together
2 Citations
2013
3 Citations
78% of Scinapse members use related papers. After signing in, all features are FREE.
References6
Newest
#1Bernhard Hellmich (University of Tübingen)H-Index: 35
#2Ana Filipa ÁguedaH-Index: 3
Last. Raashid Luqmani (University of Oxford)H-Index: 53
view all 26 authors...
Background Since the publication of the European League Against Rheumatism (EULAR) recommendations for the management of large vessel vasculitis (LVV) in 2009, several relevant randomised clinical trials and cohort analyses have been published, which have the potential to change clinical care and therefore supporting the need to update the original recommendations. Methods Using EULAR standardised operating procedures for EULAR-endorsed recommendations, the EULAR task force undertook a systemati...
48 CitationsSource
#1Christian DejacoH-Index: 27
#2Sofia Ramiro (LUMC: Leiden University Medical Center)H-Index: 27
Last. Wolfgang A. SchmidtH-Index: 32
view all 20 authors...
To develop evidence-based recommendations for the use of imaging modalities in primary large vessel vasculitis (LVV) including giant cell arteritis (GCA) and Takayasu arteritis (TAK). European League Against Rheumatism (EULAR) standardised operating procedures were followed. A systematic literature review was conducted to retrieve data on the role of imaging modalities including ultrasound, MRI, CT and [18F]-fluorodeoxyglucose positron emission tomography (PET) in LVV. Based on evidence and expe...
114 CitationsSource
#1Matthew J. Koster (Mayo Clinic)H-Index: 6
#2Eric Lawrence Matteson (Mayo Clinic)H-Index: 70
Last. Kenneth J. Warrington (Mayo Clinic)H-Index: 33
view all 3 authors...
: GCA is a chronic, idiopathic, granulomatous vasculitis of medium and large arteries. It comprises overlapping phenotypes including classic cranial arteritis and extra-cranial GCA, otherwise termed large-vessel GCA (LV-GCA). Vascular complications associated with LV-GCA may be due, in part, to delayed diagnosis, highlighting the importance of early identification and prompt initiation of effective therapy. Advancements in imaging techniques, including magnetic resonance angiography, CT angiogra...
18 CitationsSource
#1John H. Stone (Harvard University)H-Index: 70
#2Katie Tuckwell (Hoffmann-La Roche)H-Index: 8
Last. Neil Collinson (Hoffmann-La Roche)H-Index: 9
view all 16 authors...
BackgroundGiant-cell arteritis commonly relapses when glucocorticoids are tapered, and the prolonged use of glucocorticoids is associated with side effects. The effect of the interleukin-6 receptor alpha inhibitor tocilizumab on the rates of relapse during glucocorticoid tapering was studied in patients with giant-cell arteritis. MethodsIn this 1-year trial, we randomly assigned 251 patients, in a 2:1:1:1 ratio, to receive subcutaneous tocilizumab (at a dose of 162 mg) weekly or every other week...
207 CitationsSource
#1Christian Dejaco (University of Graz)H-Index: 27
#2Christina DuftnerH-Index: 24
Last. Bhaskar DasguptaH-Index: 35
view all 5 authors...
: GCA and PMR are conditions of older persons that frequently overlap. The traditional concept of GCA has focused on cranial symptoms such as headache and visual disturbance, but extra-cranial manifestations such as constitutional symptoms, polymyalgia and limb claudication have also long been recognized. These symptoms may coincide with cranial GCA, occur as an independent clinical subset [large-vessel (LV) GCA] or overlap with PMR. Imaging studies have demonstrated that up to one-third of pati...
46 CitationsSource
#1N. Bomer (Loyola University Medical Center)H-Index: 7
#2F.M. CornelisH-Index: 6
Last. Rik Jl Lories (Katholieke Universiteit Leuven)H-Index: 1
view all 10 authors...
Objective To further explore deiodinase iodothyronine type 2 ( DIO2 ) as a therapeutic target in osteoarthritis (OA) by studying the effects of forced mechanical loading on in vivo joint cartilage tissue homeostasis and the modulating effect herein of Dio2 deficiency. Methods Wild-type and C57BL/6- Dio2 −/− -mice were subjected to a forced running regime for 1 h per day for 3 weeks. Severity of OA was assessed by histological scoring for cartilage damage and synovitis. Genome-wide gene expressio...
18 CitationsSource
Cited By0
Newest