Adipose tissue macrophages: Unique polarization and bioenergetics in obesity
Abstract
Macrophages comprise a majority of the resident immune cells in adipose tissue (AT) and regulate both tissue homeostasis in the lean state and metabolic dysregulation in obesity. Since the AT environment rapidly changes based upon systemic energy status, AT macrophages (ATMs) must adapt phenotypically and metabolically. There is a distinct dichotomy in the polarization and bioenergetics of in vitro models, with M2 macrophages utilizing oxidative...
Paper Details
Title
Adipose tissue macrophages: Unique polarization and bioenergetics in obesity
Published Date
Apr 1, 2020
Journal
Volume
295
Issue
1
Pages
101 - 113
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