Genetic Variants Associated With the Onset and Progression of Primary Open-Angle Glaucoma

•Phenotypes were evaluated using the genetic risk score of primary open-angle glaucoma. •Non-intraocular pressure–related genetic variants are associated with family history. •Intraocular pressure–related genetic variants are associated with age at diagnosis. •Non-intraocular pressure–related genetic variants play an important role in onset. •Intraocular pressure–related genetic variants play an important role in progression. Purpose We sought...