Review paper
Patient-derived cancer modeling for precision medicine in colorectal cancer: beyond the cancer cell line
Abstract
Since effective immunotherapeutic agents such as immune checkpoint blockade to treat cancer have emerged, the need for reliable preclinical cancer models that can evaluate and discover such drugs became stronger than ever before. The traditional preclinical cancer model using a cancer cell line has several limitations to recapitulate intra-tumor heterogeneity and in-vivo tumor activity including interactions between tumor-microenvironment. In...
Paper Details
Title
Patient-derived cancer modeling for precision medicine in colorectal cancer: beyond the cancer cell line
Published Date
Mar 25, 2020
Journal
Volume
21
Issue
6
Pages
495 - 502
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