Gains of EPOR and ERG genes in adult erythroleukaemia

Acute erythroid leukaemia (AEL) is a particular form of acute myeloid leukaemia (AML). It represents about 5% of AMLs and has a poor prognosis. Two subtypes are distinguished. The most frequent is M6a, characterised by an accumulation of erythroblasts and myeloblasts in the bone marrow, while M6b, in which the bone marrow is invaded only by erythroblasts at various stages of differentiation, is extremely rare. In the last classification of the...