CIC is a critical regulator of neuronal differentiation
Volume: 5, Issue: 9
Published: May 7, 2020
Abstract
Capicua (CIC), a member of the high mobility group–box (HMG-box) superfamily of transcriptional repressors, is frequently mutated in human oligodendrogliomas. However, its functions in brain development and tumorigenesis remain poorly understood. Here, we report that brain-specific deletion of Cic compromises developmental transition of neuroblasts to immature neurons in mouse hippocampus and compromises normal neuronal differentiation. Combined...
Paper Details
Title
CIC is a critical regulator of neuronal differentiation
Published Date
May 7, 2020
Volume
5
Issue
9
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