Patterns matter part 2: Chitosan oligomers with defined patterns of acetylation

Chitosans are linear, binary co-polymers of glucosamine and N-acetylglucosamine residues with interesting material properties and promising biological activities. Many of the biological activities of chitosan polymers are thought to be conveyed by their oligomeric breakdown products generated in situ by the action of sequence-specific chitosan hydrolases yielding partially acetylated chitosan oligosaccharides (paCOS) with partially or fully...