Pregabalin adjunctive therapy for focal onset seizures in children 1 month to <4 years of age: A double‐blind, placebo‐controlled, video‐electroencephalographic trial

Objective To evaluate the efficacy and safety of pregabalin as adjunctive treatment for children (aged 1 month‐<4 years) with focal onset seizures (FOS) using video‐electroencephalography (V‐EEG). Methods This randomized, placebo‐controlled, international study included V‐EEG seizure monitoring (48‐72 hours) at baseline and over the last 3 days of 14‐day (5‐day dose escalation; 9‐day fixed dose) double‐blind pregabalin treatment (7 or 14...