Bone Disease in Patients with Ehlers–Danlos Syndromes

To summarize the bone findings, mainly bone mass and fracture risk, in Ehlers–Danlos syndromes (EDS). Low bone mineral density and fractures seem to be frequent in some of the rare EDS types (kyphoscoliotic, arthrochalasia, spondylodysplastic, and classic-like EDS). For the more prevalent hypermobile and classic EDS types, some case–control studies found mildly decreased bone mineral density, but it was not clear that fracture rates were...