Regional Amyloid Accumulation and White Matter Integrity in Cognitively Normal Individuals
Abstract
Background:Recent studies have shown that amyloid-β (Aβ) burden influenced white matter (WM) integrity before the onset of dementia. Objective:To assess whether the effects of Aβ burden on WM integrity in cognitively normal (CN) individuals were regionally specific. Methods:Our cohort consisted of 71 CNs from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) database who underwent both AV45 amyloid-PET and diffusion tensor imaging....
Paper Details
Title
Regional Amyloid Accumulation and White Matter Integrity in Cognitively Normal Individuals
Published Date
Apr 21, 2020
Volume
74
Issue
4
Pages
1261 - 1270
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