Lipid analogs reveal features critical for hemolysis and diminish granadaene mediated Group B Streptococcus infection
Abstract
Although certain microbial lipids are toxins, the structural features important for cytotoxicity remain unknown. Increased functional understanding is essential for developing therapeutics against toxic microbial lipids. Group B Streptococci (GBS) are bacteria associated with preterm births, stillbirths, and severe infections in neonates and adults. GBS produce a pigmented, cytotoxic lipid, known as granadaene. Despite its importance to all...
Paper Details
Title
Lipid analogs reveal features critical for hemolysis and diminish granadaene mediated Group B Streptococcus infection
Published Date
Mar 20, 2020
Journal
Volume
11
Issue
1
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