Solubility, thermodynamics and molecular interaction studies of delafloxacin in environmental friendly ionic liquids

In the current study, solubility, thermodynamics and molecular interaction of delafloxacin (DFLX) in water, ethanol, transcutol-HP (THP) and three different alkylimidazolium based ionic liquids were conducted at temperature range “T = 298.2 K to 318.2 K” and pressure “p = 0.1 MPa”. The solid phase characterization of initial and equilibrated DFLX by DSC, FTIR and PXRD confirmed no significant change in crystallinity of the drug. The maximum mole...