Simultaneous multiple allelic replacement in the malaria parasite enables dissection of PKG function
Abstract
Over recent years, a plethora of new genetic tools has transformed conditional engineering of the malaria parasite genome, allowing functional dissection of essential genes in the asexual and sexual blood stages that cause pathology or are required for disease transmission, respectively. Important challenges remain, including the desirability to complement conditional mutants with a correctly regulated second gene copy to confirm that observed...
Paper Details
Title
Simultaneous multiple allelic replacement in the malaria parasite enables dissection of PKG function
Published Date
Mar 16, 2020
Journal
Volume
3
Issue
4
Pages
e201900626 - e201900626
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Notes
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