miR‐21‐3p regulates AGE/RAGE signalling and improves diabetic atherosclerosis

To explore the effects of miR‐21‐3p on diabetic atherosclerosis. Using enzyme‐linked immunosorbent assay (ELISA), we also detected the levels of soluble receptor for advanced glycation endproducts RAGE (sRAGE) in the cellular supernatant of vascular endothelial cells after transfecting them with adenovirus vector having miR‐21‐3p mimic or inhibitor. We found decrease in the expression levels of miR‐21‐3p in vascular endothelial cells (VECs)...