Characterization of HIV-1 uncoating in human microglial cell lines
Abstract
Background After viral fusion with the cell membrane, the conical capsid of HIV-1 disassembles by a process called uncoating. Previously we have utilized the CsA washout assay, in which TRIM-CypA mediated restriction of viral replication is used to detect the state of the viral capsid, to study the kinetics of HIV-1 uncoating in owl monkey kidney (OMK) and HeLa cells. Here we have extended this analysis to the human microglial cell lines CHME3...
Paper Details
Title
Characterization of HIV-1 uncoating in human microglial cell lines
Published Date
Mar 6, 2020
Journal
Volume
17
Issue
1
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