Sertraline induces DNA damage and cellular toxicity in Drosophila that can be ameliorated by antioxidants
Abstract
Sertraline hydrochloride is a commonly prescribed antidepressant medication that acts by amplifying serotonin signaling. Numerous studies have suggested that children of women taking sertraline during pregnancy have an increased risk of developmental defects. Resolving the degree of risk for human fetuses requires comprehensive knowledge of the pathways affected by this drug. We utilized a Drosophila melanogaster model system to assess the...
Paper Details
Title
Sertraline induces DNA damage and cellular toxicity in Drosophila that can be ameliorated by antioxidants
Published Date
Mar 11, 2020
Journal
Volume
10
Issue
1
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