Toward a Better Mechanistic Understanding of Critical Illness: Endothelial, Microvascular and Coagulation Dysfunction

Joseph A. Carcillo, MD, EditorView Large Image Figure ViewerDownload Hi-res image Download (PPT)Few physiologic processes are closer to the “heart and soul” of critical care practice as tissue perfusion. Matching oxygen delivery to metabolic demand is arguably the quintessential physiologic essence of the practice of critical care medicine and one of the central daily struggles of every intensivist. It is no surprise that a deep understanding of...