Biomaterials and biocompatibility: An historical overview

Published on Mar 20, 2020in Journal of Biomedical Materials Research Part A3.221
· DOI :10.1002/JBM.A.36930
Elia Marin16
Estimated H-index: 16
(Kyoto Institute of Technology),
Francesco Boschetto5
Estimated H-index: 5
(Kyoto Institute of Technology),
Giuseppe Pezzotti36
Estimated H-index: 36
This review focuses on the characteristics and applications of biomaterials through the ages, ranging from the prehistoric times to the beginning of the era of modern medicine, which has been arbitrarily set to the middle of the 19th century, when aseptic procedures, antiseptic substances and modern anaesthetics were developed. After a brief discussion on the definition of "biomaterial" from an historical point of view and a short introduction on the general history of surgery and dentistry, each material or class of materials will be presented with references listed in chronological order and, where possible, with their real, scientifically demonstrated effects on biological tissues. Particular attention has been given to references that are nowadays considered spurious or affected by translation errors or other kinds of biases. This article is protected by copyright. All rights reserved.
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