The epidemiology of regular opioid use and its association with mortality: Prospective cohort study of 466 486 UK biobank participants

Opioids have, at most, small benefits for non-cancer pain in the medium and long-term but there is good evidence that they cause harm. The current study describes the characteristics and clinical status of people taking regular opioids in Great Britain and determines whether use is associated with mortality risk.An analysis of participants in UK Biobank, a prospective population-based study. At recruitment (2006-10) participants reported...