A randomized, placebo-controlled, phase II study of obeticholic acid for primary sclerosing cholangitis
Abstract
Primary sclerosing cholangitis (PSC) is a rare, cholestatic liver disease with no currently approved therapies. Obeticholic acid (OCA) is a potent farnesoid X receptor (FXR) agonist approved for the treatment of primary biliary cholangitis. We investigated the efficacy and safety of OCA in patients with PSC.AESOP was a phase II, randomized, double-blind, placebo-controlled, dose-finding study. Eligible patients were 18 to 75 years of age with a...
Paper Details
Title
A randomized, placebo-controlled, phase II study of obeticholic acid for primary sclerosing cholangitis
Published Date
Jul 1, 2020
Journal
Volume
73
Issue
1
Pages
94 - 101
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