Diabetes-associated genetic variation in TCF7L2 alters pulsatile insulin secretion in humans
Abstract
BACKGROUND. Metabolic disorders such as type 2 diabetes have been associated with a decrease in insulin pulse frequency and amplitude. We hypothesized that the T allele at rs7903146 in TCF7L2, previously associated with β cell dysfunction, would be associated with changes in these insulin pulse...
Paper Details
Title
Diabetes-associated genetic variation in TCF7L2 alters pulsatile insulin secretion in humans
Published Date
Apr 9, 2020
Journal
Volume
5
Issue
7
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