Testosterone is sequestered in dysfunctional adipose tissue, modifying androgen-responsive genes
Abstract
The recognized association between male hypogonadism and obesity has multifactorial implications on adipose tissue (AT) physiology. The fat solubility of testosterone (T) suggests a sequestration process in fat depots, leading to reduced circulating levels of T in obesity. Several evidence suggest that steroids play a two-sided inhibitory role on adipogenesis by locally decreasing lipid accumulation and by stimulating lipolysis. The current...
Paper Details
Title
Testosterone is sequestered in dysfunctional adipose tissue, modifying androgen-responsive genes
Published Date
Mar 17, 2020
Volume
44
Issue
7
Pages
1617 - 1625
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