Altered expression of 17‑β‑hydroxysteroid dehydrogenase type�2 and its prognostic significance in non‑small cell lung cancer

Published: Mar 19, 2020
Abstract
Numerous studies have reported that oestrogens may contribute to the development of non‑small cell lung cancer (NSCLC). Although different steroidogenic enzymes have been detected in the lung, the precise mechanism leading to an exaggerated accumulation of active oestrogens in NSCLC remains unexplained. 17‑β‑Hydroxysteroid dehydrogenase type 2 (HSD17B2) is an enzyme involved in oestrogen and androgen inactivation by converting 17‑β‑oestradiol...
Paper Details
Title
Altered expression of 17‑β‑hydroxysteroid dehydrogenase type�2 and its prognostic significance in non‑small cell lung cancer
Published Date
Mar 19, 2020
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