Accelerate development of topical cream drug product using a common platform base formulation

Volume: 25, Issue: 6, Pages: 767 - 778
Published: Mar 25, 2020
Abstract
The aim of this work was to identify stable topical platform cream formulations (placebo creams without active drug substance) using the quality attributes of cream consistency, droplet size distribution (<1 μm), and separation or instability index of <0.1 to accelerate the development of topical cream drug product. The formulations were developed with six emulsifier systems that were screened in three different solvent systems across a range of...
Paper Details
Title
Accelerate development of topical cream drug product using a common platform base formulation
Published Date
Mar 25, 2020
Volume
25
Issue
6
Pages
767 - 778
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