Rewiring of gene networks underlying mite allergen‐induced CD4 + Th‐cell responses during immunotherapy
Abstract
Background Multiple regulatory mechanisms have been identified employing conventional hypothesis‐driven approaches as contributing to allergen‐specific immunotherapy outcomes, but understanding of how these integrate to maintain immunological homeostasis is incomplete. Objective To explore the potential for unbiased systems‐level gene co‐expression network analysis to advance understanding of immunotherapy mechanisms. Methods We profiled...
Paper Details
Title
Rewiring of gene networks underlying mite allergen‐induced CD4 + Th‐cell responses during immunotherapy
Published Date
Apr 14, 2020
Journal
Volume
75
Issue
9
Pages
2330 - 2341
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