Synthesis, characterization, and antitumor activity of a new iron-rifampicin complex: A novel prospective antitumor drug

Rifampicin is a semi-synthetic derivative of rifamycin. It has a broad antibacterial activity. Iron is the most plentiful transition metal in human body. It is a crucial nutrient needed for numerous essential cellular functions. The present study is a trial to develop a novel antitumor candidate depending on formation of a complex between iron and rifampicin. After successful preparation, the resultant complex was characterized. Then its...