Small molecules that target the ubiquitin system

Volume: 48, Issue: 2, Pages: 479 - 497
Published: Mar 20, 2020
Abstract
Eukaryotic life depends upon the interplay between vast networks of signaling pathways composed of upwards of 109–1010 proteins per cell. The integrity and normal operation of the cell requires that these proteins act in a precise spatial and temporal manner. The ubiquitin system is absolutely central to this process and perturbation of its function contributes directly to the onset and progression of a wide variety of diseases, including...
Paper Details
Title
Small molecules that target the ubiquitin system
Published Date
Mar 20, 2020
Volume
48
Issue
2
Pages
479 - 497
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