Crucial role for lung iron level and regulation in the pathogenesis and severity of asthma

Volume: 55, Issue: 4, Pages: 1901340 - 1901340
Published: Mar 17, 2020
Abstract
Accumulating evidence highlights links between iron regulation and respiratory disease. Here, we assessed the relationship between iron levels and regulatory responses in clinical and experimental asthma.We show that cell-free iron levels are reduced in the bronchoalveolar lavage (BAL) supernatant of severe or mild-moderate asthma patients and correlate with lower forced expiratory volume in 1 s (FEV1). Conversely, iron-loaded cell numbers were...
Paper Details
Title
Crucial role for lung iron level and regulation in the pathogenesis and severity of asthma
Published Date
Mar 17, 2020
Volume
55
Issue
4
Pages
1901340 - 1901340
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