Telomere length alterations and ATRX/DAXX loss in pituitary adenomas
Abstract
Telomeres are nucleoprotein complexes located at the termini of eukaryotic chromosomes that prevent exonucleolytic degradation and end-to-end chromosomal fusions. Cancers often have critically shortened, dysfunctional telomeres contributing to genomic instability. Telomere shortening has been reported in a wide range of precancerous lesions and invasive carcinomas. However, the role of telomere alterations, including the presence of alternative...
Paper Details
Title
Telomere length alterations and ATRX/DAXX loss in pituitary adenomas
Published Date
Aug 1, 2020
Journal
Volume
33
Issue
8
Pages
1475 - 1481
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Notes
History