Nanoparticles based on the zwitterionic pillar[5]arene and Ag⁺: synthesis, self-assembly and cytotoxicity in the human lung cancer cell line A549

For the first time, stable pillar[5]arene/Ag + nanoparticles, consisting of water-soluble pillar[5]arene containing γ-sulfobetaine fragments and Ag + ions without Ag–Ag bonds, were synthesized and characterized. The pillar[5]arene/Ag + (ratio 1:10) nanoparticles obtained were cubic with a rib length of 100 nm and are less cytotoxic than Ag + ions. The survival of the A549 model cells in the presence of pillar[5]arene/Ag + (1:10) nanoparticles at...