Membrane domains beyond the reach of microscopy

The concept of lipid rafts describes the lateral compartmentalization of cellular membranes into domains of different compositions and physical properties (1Levental, I., K. R., Levental, and F. A., Heberle, . 2020. Lipid rafts: controversies resolved, mysteries remain. Trends Cell Biol. February 19, 2020. doi: https://doi.org/10.1016/j.tcb.2020.01.009.Google Scholar). Raft themselves are relatively tightly packed domains enriched in sterols,...