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Cytopathology in Endobronchial Ultrasound‐Guided Transbronchial Needle Aspiration of Mediastinal and Hilar Lymph Nodes

Published on Mar 20, 2020
· DOI :10.1002/9781119233961.CH15
Christopher M. Kniese , Ali I. Musani22
Estimated H-index: 22
Abstract
  • References (27)
  • Citations (0)
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References27
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2 CitationsSource
#1Lauren N. PearsonH-Index: 2
#2Rachel E. FactorH-Index: 17
Last. Robert L. SchmidtH-Index: 26
view all 6 authors...
Objective: Rapid on-site evaluation (ROSE) has been shown to improve adequacy rates and reduce needle passes. ROSE is often performed by cytopathologists who have limited availability and may be costlier than alternatives. Several recent studies examined the use of alternative evaluators (AEs) for ROSE. A summary of this information could help inform guidelines regarding the use of AEs. The objective was to assess the accuracy of AEs compared to cytopathologists in assessing the adequacy of spec...
2 CitationsSource
#1Onur Fevzi ErerH-Index: 3
#2Serhat ErolH-Index: 4
Last. Serir OzkanH-Index: 5
view all 6 authors...
Source
#1Jonas J. Heymann (NewYork–Presbyterian Hospital)H-Index: 11
#2William A. Bulman (NewYork–Presbyterian Hospital)H-Index: 2
Last. Anjali Saqi (NewYork–Presbyterian Hospital)H-Index: 11
view all 13 authors...
50 CitationsSource
#1Samantha HerathH-Index: 1
#2Wendy A. Cooper (USYD: University of Sydney)H-Index: 24
The immunohistochemical expression of Programmed Death Ligand (PD-L1) predicts responses to PD-1/PD-L1 inhibitors in non-small cell lung cancer (NSCLC). PD-L1 testing is currently only recommended on tissue specimens; however, in many patients, cytology samples are the only specimens available. The introduction of the novel 19G “core-biopsy” needle has revolutionized the utility of endobronchial USS-guided biopsy (EBUS) by providing solid tissue “microbiopsies” rather than traditional liquid cyt...
1 CitationsSource
#2Sahajal DhooriaH-Index: 17
Last. Ritesh Agarwal DmH-Index: 39
view all 4 authors...
Background Whether the use of rapid on-site cytologic evaluation (ROSE) increases the diagnostic yield of transbronchial needle aspiration (TBNA) remains unclear. This article is a systematic review of studies describing the utility of ROSE in subjects undergoing TBNA. Methods The study included a systematic review of the PubMed, Embase, and Scopus databases for randomized controlled trials investigating the diagnostic yield of conventional transbronchial needle aspiration (c-TBNA) or endobronch...
12 CitationsSource
#1Jonas J. Heymann (NewYork–Presbyterian Hospital)H-Index: 11
#2William A. Bulman (NewYork–Presbyterian Hospital)H-Index: 2
Last. Anjali Saqi (NewYork–Presbyterian Hospital)H-Index: 11
view all 13 authors...
34 CitationsSource
#1Deepali Jain (AIIMS: All India Institute of Medical Sciences)H-Index: 19
#2Timothy Craig Allen (UTMB: University of Texas Medical Branch)H-Index: 16
Last. Marina Vivero (Harvard University)H-Index: 13
view all 20 authors...
Context.— Endobronchial ultrasound–guided transbronchial needle aspiration (EBUS-TBNA) has emerged as a very useful tool in the field of diagnostic respiratory cytology. Rapid on-site evaluation (ROSE) of EBUS-TBNA not only has the potential to improve diagnostic yield of the procedure but also to triage samples for predictive molecular testing to guide personalized treatments for lung cancer. Objective.— To provide an overview of the current status of the literature regarding ROSE of EBUS-TBNA ...
20 CitationsSource
#1Jinwoo Lee (SNU: Seoul National University)H-Index: 70
#2Sun Mi Choi (SNU: Seoul National University)H-Index: 14
Last. Young Sik Park (SNU: Seoul National University)H-Index: 15
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Abstract Background Diagnosis of intrathoracic tuberculosis (TB) lymphadenitis remains a challenge because of difficulties in obtaining adequate tissue and the lack of a sensitive test. Recently, Xpert MTB/RIF assay is being used for rapid diagnosis of pulmonary TB, but it has not yet been widely validated in intrathoracic TB lymphadenitis. The aim of this study was to assess the additional role of Xpert MTB/RIF in diagnosing intrathoracic TB lymphadenitis using endobronchial ultrasound-guided t...
7 CitationsSource
#1Sun Mi Choi (Seoul National University Hospital)H-Index: 5
#2Ae Ra Lee (Seoul National University Hospital)H-Index: 1
Last. Young Sik Park (Seoul National University Hospital)H-Index: 7
view all 13 authors...
Background Rapid on-site evaluation (ROSE) for endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) has been advocated to qualitatively diagnose biopsy samples. However, adequate ROSE criteria during EBUS-TBNA are unclear. The aim of this study was to determine adequacy criteria of ROSE in EBUS-TBNA samples and suggest an appropriate algorithm. Methods Patients who underwent EBUS-TBNA for nodal evaluation between March and July 2013 at Seoul National University Hospital w...
7 CitationsSource
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