Hyperfunction of the stress response system and novelty‐induced hyperactivity correlate with enhanced cocaine‐induced conditioned place preference in NCAM‐deficient mice

Volume: 26, Issue: 2
Published: Mar 2, 2020
Abstract
Several studies in humans and rodents suggest an association between impulsivity and activity of the stress response on the one hand and addiction vulnerability on the other. The neural cell adhesion molecule (NCAM) has been related to several neuropsychiatric disorders in humans. Constitutively NCAM-deficient (-/-) mice display enhanced novelty-induced behavior and hyperfunction of the hypothalamic-pituitary-adrenal axis. Here we hypothesize...
Paper Details
Title
Hyperfunction of the stress response system and novelty‐induced hyperactivity correlate with enhanced cocaine‐induced conditioned place preference in NCAM‐deficient mice
Published Date
Mar 2, 2020
Volume
26
Issue
2
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