Integration of luminal pressure and signalling in tissue self-organization
Abstract
Many developmental processes involve the emergence of intercellular fluid-filled lumina. This process of luminogenesis results in a build up of hydrostatic pressure and signalling molecules in the lumen. However, the potential roles of lumina in cellular functions, tissue morphogenesis and patterning have yet to be fully explored. In this Review, we discuss recent findings that describe how pressurized fluid expansion can provide both mechanical...
Paper Details
Title
Integration of luminal pressure and signalling in tissue self-organization
Published Date
Mar 1, 2020
Journal
Volume
147
Issue
5
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