Sex-specific adipose tissue imprinting of regulatory T cells
Abstract
Adipose tissue is an energy store and a dynamic endocrine organ1,2. In particular, visceral adipose tissue (VAT) is critical for the regulation of systemic metabolism3,4. Impaired VAT function—for example, in obesity—is associated with insulin resistance and type 2 diabetes5,6. Regulatory T (Treg) cells that express the transcription factor FOXP3 are critical for limiting immune responses and suppressing tissue inflammation, including in the...
Paper Details
Title
Sex-specific adipose tissue imprinting of regulatory T cells
Published Date
Feb 26, 2020
Journal
Volume
579
Issue
7800
Pages
581 - 585
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Notes
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