Smoking causes induction of micronuclei and other nuclear anomalies in cervical cells

Smoking is an independent cause of cervical cancer, which is the 4th most common malignancy in women. It is currently not known if tobacco consumption causes chromosomal damage (which is a hallmark of human cancer) in cervical cells and if age and the hormonal status have an impact on tobacco induced genetic instability in the cervix. We conducted a study with pre- and post-menopausal women smokers and never-smokers (25/group). Smokers consumed...