Integrated transcriptomic correlation network analysis identifies COPD molecular determinants
Abstract
Chronic obstructive pulmonary disease (COPD) is a complex and heterogeneous syndrome. Network-based analysis implemented by SWIM software can be exploited to identify key molecular switches - called "switch genes" - for the disease. Genes contributing to common biological processes or defining given cell types are usually co-regulated and co-expressed, forming expression network modules. Consistently, we found that the COPD correlation network...
Paper Details
Title
Integrated transcriptomic correlation network analysis identifies COPD molecular determinants
Published Date
Feb 25, 2020
Journal
Volume
10
Issue
1
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