Design and methodology challenges of environment-wide association studies: A systematic review
Abstract
Environment-wide association studies (EWAS) are an untargeted, agnostic, and hypothesis-generating approach to exploring environmental factors associated with health outcomes, akin to genome-wide association studies (GWAS). While design, methodology, and replicability standards for GWAS are established, EWAS pose many challenges. We systematically reviewed published literature on EWAS to categorize scope, impact, types of analytical approaches,...
Paper Details
Title
Design and methodology challenges of environment-wide association studies: A systematic review
Published Date
Apr 1, 2020
Journal
Volume
183
Pages
109275 - 109275
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