Anilinopyrazines as potential mitochondrial uncouplers
Volume: 30, Issue: 8, Pages: 127057 - 127057
Published: Apr 1, 2020
Abstract
Mitochondrial protonophores transport protons through the mitochondrial inner membrane into the matrix to uncouple nutrient oxidation from ATP production thereby decreasing the proton motive force. Mitochondrial uncouplers have beneficial effects of decrease reactive oxygen species generation and have the potential for treating diseases such as obesity, neurodegenerative diseases, non-alcoholic fatty liver disease (NAFLD), diabetes, and many...
Paper Details
Title
Anilinopyrazines as potential mitochondrial uncouplers
Published Date
Apr 1, 2020
Volume
30
Issue
8
Pages
127057 - 127057
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