Novel synthesis of mussel inspired and Fe3+ induced pH-sensitive hydrogels: Adhesion, injectable, shapeable, temperature properties, release behavior and rheological characterization

A novel EGCG-loaded DCKGM-CCKGM-Fe3+hydrogel was prepared by Dopamine-carboxymethyl konjac glucomannan (DCKGM) and an l-Cysteine-carboxymethyl konjac glucomannan (CCKGM) with Fe3+ as a cross-linking agent. Due to the dynamic property of Fe3+-phenolic hydroxyl coordination bond and intermolecular hydrogen bonding, the resultant hydrogel featured injectable, adhesive, temperature and pH-sensitive properties. The mechanisms were characterized using...