Synthesis of Lactams via Ir-Catalyzed C–H Amidation Involving Ir-Nitrene Intermediates

Volume: 85, Issue: 6, Pages: 4430 - 4440
Published: Feb 27, 2020
Abstract
x-membered lactams were synthesized via either an amidation of sp3 C–H bonds or an electrophilic substitution of arenes via Ir-nitrene intermediates. With the employment of a readily available iridium catalyst in dichloromethane or hexafluoro-2-propanol, a wide range of lactams were synthesized in good to excellent yields with high...
Paper Details
Title
Synthesis of Lactams via Ir-Catalyzed C–H Amidation Involving Ir-Nitrene Intermediates
Published Date
Feb 27, 2020
Volume
85
Issue
6
Pages
4430 - 4440
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